If you’re ready to see differences in your workout regimen, you may be curious how muscle peptides are associated with lean muscle gain and strength building. As a locally owned and operated company, Muscle Peptides Australia is committed to helping our clients across Australia achieve their fitness goals. Contact us to unlock your body’s real potential.
Yes, Ipamorelin can help you lose weight. But, if you are not exercising, and aren’t eating well, it can only do so much. There is no magical supplement which will undo laziness and a horrible diet – keep this in mind. When using it for fat loss, make sure you are exercising. Doing so will naturally increase weight loss results, as you are going to burn more calories, along with the caloric deficit you are already on, for greater results. Further, your diet matters. If you are eating 5000 calories of junk per day, no supplement will help you lose weight – no matter how potent it claims to be!
ADV Research ADV-17 Post Cycle Therapy PRODUCT STRENGTH (CONCENTRATION): 30MG/ML KEY BENEFITS Raises testosterone levels Lowers estrogen levels Raises luteinizing hormone (LH) levels Lowers cortisol levels Enhances recovery speed Promotes vascularity (hardening and drying out) Increases libido Inhibits gynecomastia (male breast enlargement) Promotes fat loss Not liver toxic GENDER SUITABILITY ADV-17 is suitable for use by males. Females should not…

CJC-1295 increases the production of growth hormone as well as IGF-1 – which has anabolic effects in adults. However, it does not increase the levels of prolactin – high levels of which can create impotence and mental health problems in men. By increasing these two hormones, it enhances protein production in the body, which in turn, boosts muscle mass. It also induces lipolysis – the breakdown of fat tissue, boosts recovery from injuries, increases bone density, and also reduces aging factors like skin wrinkles. It can also stimulate cell growth, due to which it can be used to treat withered tissue or organs.
GHRP-6 is normally always manufactured as lyophilized (freeze-dried) powder contained in vials in amounts of 5mg. Some companies might manufacture amounts greater or lesser than 5mg per vial, but the standard is generally 5mg/vial. The lyophilized powder contained within the vial will need to be reconstituted with bacteriostatic water in order for it to be injected. After reconstitution, the solution must then be refrigerated in storage. If left in hot environments or in room temperature environments for extended periods of time, the protein structure will degrade and become ineffective. For reconstitution, users will typically mix 3ml of bacteriostatic water with the powder gently. However, users can and do frequently reconstitute the powder with less (or more) water which will yield different concentrations of GHRP-6. For example, reconstitution of 5mg of powder with 3ml of water will yield GHRP-6 doses of 166mcg per 0.1ml (or 10iu on an insulin syringe).
Sufficient data was not available on the therapeutic use of non-steroidal SARMs. No SARMs were currently marketed, however enobosarm was undergoing clinical trials in a range of medical conditions such as cachexia, sarcopenia, osteoporosis and frailty. These conditions require medical diagnosis, monitoring and management, i.e. scheduling factors for Schedule 4.
Technically, it is a “protein-peptide hormone” which means that it consists of 70 amino acids bonded together. Just like the peptides I’ve written about in the past, this means that it must be injected, because otherwise IGF-1 simply degrades in the gut, rendering it useless. Your own human growth hormone release promotes the synthesis of IGF-1 in your liver (and to smaller amounts, synthesis of IGF-1 by your muscles), your liver and muscles then synthesize IGF-1 and then, in the case of your liver, subsequently package the IGF-1 with binding proteins for transport into the blood. In a type of anabolic positive-feedback loop, IGF-1 then further increases growth hormone’s anabolic effects.
The discovery of the role of Tβ4 in the process of immune regulation has lead to its use as a valuable therapeutic agent. Tβ4 has been used in the treatment of HIV, AIDS, Influenza, colds, and various infections. It has been utilized in the management of various inflammatory conditions, as well as part of treatment following heart attack due to its cardio and neuroprotective effects.
Peptide can be defined as the chain of 50 or lower amino acids with amino carboxyl end, though there are some exceptions to the rule. Bodybuilding peptides are actually closely related to the proteins, differing only by amount of amino acids that are present in the chain. Generally people think that proteins and peptides are the same and so they use them interchangeably. The confusion arises because insulin serves as both a protein as well as peptide. Peptides can basically be natural in their origin and found in regular daily diet.

Results: After a single injection of CJC 1295, there were dose dependent increases in mean plasma GH concentrations by 2- to 10-fold for 6 d or more and in mean plasma IGF-I concentrations by 1.5- to 3-fold for 9–11 d. The estimated half-life of CJC 1295 was 5.8–8.1 d. After multiple CJC 1295 doses, mean IGF-I levels remained above baseline for up to 28 d. No serious adverse reactions were reported.
If GHRP-6 is powerful for growth hormone release, this peptide is even stronger, albeit slightly so. GHRP-2 is used for similar purposes as the other compound. But it does not fire up appetite as the other peptide is known to do. This may make it more ideal for people interested in improving lean muscle mass. Furthermore, it does not desensitize when taken in low doses without observing breaks as required for other peptides.
ADV Research ADV-516 30mgs/ml Will de dispatched Friday 15th June – Pre Orders Now KEY BENEFITS Speed up fat burning by enhancing your fatty acid metabolism Trigger the same genetic paths as using energy during exercise Supercharge your strength, energy, and endurance Hold onto muscle tissue while dieting – non-catabolic Store less carbs and fat as adipose tissue Grow a…
The qualitative microscopic analysis of the GHRP-6 responsive wounds indicated that the peptide seems to primarily reduce both local hypercellularity associated with the cartilage perichondrium cells and the resulting ECM accumulation (Figures 6(a) and 6(b)). Accordingly, their SEI () appeared largely different () as compared to the placebo samples group (). It is notorious, however, that those GHRP-6 nonresponsive wounds () that evolved to HTS exhibited similar microscopic appearance (not shown) and SEI values as compared to placebo control wounds (Table 3).

Lactating nipples: GHRP-6 side effects include that of increased Prolactin secretion, which can result in lactation from the nipples. This is, however, a rare occurrence but it can happen in sensitive individuals. GHRP-6 exhibits the ability to induce secretion of Cortisol and Prolactin[3], but studies have shown that the Prolactin and Cortisol increases in most test subjects were not altered at all at GHRP-6 doses of 100mcg or less[4] [5]. Doses above 100mcg are said to increase Prolactin secretion, though minimally, and at these minimal levels lactation should not present itself. However, some users have reported lactation which can be the result of a sensitive individual or the result of much higher doses of GHRP-6. Prolactin can be lowered through the use of a Prolactin antagonist such as Cabergoline, Pramipexole, Bromocriptine, and even vitamin B6.

The other submission commented on the consideration to place AOD-9604 in Appendix D. The submission supported listing in Schedule 4, but raised concerns that listing the substance in Appendix D would limit any future development work, including clinical trials that are currently being conducted on the substance. The submitter notes that there are currently 5 clinical trials notified to the TGA using this substance , with these approved clinical trials going ahead on the basis that the substance is safe for human use. Inclusion in Appendix D may place unnecessary burden on those conducting these clinical trials.
GHRP-6 is normally always manufactured as lyophilized (freeze-dried) powder contained in vials in amounts of 5mg. Some companies might manufacture amounts greater or lesser than 5mg per vial, but the standard is generally 5mg/vial. The lyophilized powder contained within the vial will need to be reconstituted with bacteriostatic water in order for it to be injected. After reconstitution, the solution must then be refrigerated in storage. If left in hot environments or in room temperature environments for extended periods of time, the protein structure will degrade and become ineffective. For reconstitution, users will typically mix 3ml of bacteriostatic water with the powder gently. However, users can and do frequently reconstitute the powder with less (or more) water which will yield different concentrations of GHRP-6. For example, reconstitution of 5mg of powder with 3ml of water will yield GHRP-6 doses of 166mcg per 0.1ml (or 10iu on an insulin syringe).
Total RNA was purified according to TRI Reagent standard procedure (Sigma, USA), following digestion with RQ1 DNase I (Promega, USA) to remove contaminating genomic DNA. Afterward, 500 ng of DNA-free RNA was reverse transcribed using Omniscript RT kit (Qiagen, Germany) with oligo-dT primer. The RT reaction was performed at 42°C for 60 min. PCR mixtures contained 1 μL cDNA, 1 μL of each primer (10 μM), and 12.5 μL 2x Taq MasterMix (Qiagen, Germany) in a final volume of 25 μL. Specific sense and antisense primers, annealing temperatures, and number of repeating cycles for both studies are referred to in Table 1. Amplifying conditions were performed as follows: a first step of 95°C for 5 minutes, thereafter repeating cycles comprised of 95°C for 30 seconds, specific annealing temperature for 30 seconds and 72°C for 30 seconds, and a final extension step of 5 minutes at 72°C. PCR bands (8 μL of PCR product plus 2 μL of gel loading buffer) were resolved on 1.5% (w/v) agarose gel electrophoresis and visualized under ultraviolet light subsequent to being stained with ethidium bromide. PCR products were quantified using the Kodak ID 3.6 software package (Kodak Inc, USA). Beta-2 microglobulin was used as housekeeping gene for normalization.
GHRP-6 is a peptide from the category of growth hormone releasing peptides, ie growth hormone-releasing peptides. The most frequent use of these peptides is an extreme increase in the body's growth hormone production. The main application area of GHRP-6 is an increase in growth hormone levels, which also results in an increase in IGF1 levels. This also radically supports fat loss as well as muscle building. In general, GHRPs are used as an alternative to growth hormones or even combined with growth hormones to achieve virtually a double effect, synthetic and natural. Reasons for favoring GHRP-6 versus other GHRPs are its appetite-stimulating effect, although present, but weaker than GHRP-2 and its ability to reduce inflammation and assist healing of injuries such as tendonitis. Products are sold strictly for research purposes only, not for human consumption!
The response to GHSs is not gender related, except during puberty, when girls exhibit a greater response than do boys. The GH responses to both GHSs and ghrelin are similar during the early-follicular, late-follicular, and luteal phases of the menstrual cycle, suggesting that they are not affected by changes in estrogen levels. However, estrogen as well as estrogen-progestin supplementation enhances the GH response to ghrelin after menopause.
Cerebrolysin—also known as FPE 1070—is a synthetic nootropic drug. Nootropic drugs are substances that enhance cognitive functions such as memory, creativity, and motivation in otherwise healthy individuals. This peptide is extremely small, allowing it to penetrate the blood-brain barrier and act directly on the neurons of the central nervous system. Cerebrolysin has been found to improve the metabolic activity of brain tissue, shield neurons from harmful substances, and stimulate the peripheral and central nervous systems. In addition to its utility as a nootropic substance, the drug has potential as part of a treatment plan addressing Alzheimer’s disease, stroke, and moderate to severe head injury.

Django Nathan, a medical doctor with a degree in molecular biology and genetics, takes peptides because of his busy lifestyle: "Quite a few doctors I know are using them because they have so many beneficial effects and so few side effects. We're not elite athletes – we live rushed lives that can involve 70 hour weeks so staying fit and getting good sleep is essential – and peptides aid that."
Healthy male Wistar rats (250–270 g) were purchased from the National Center for Animal Breeding (CENPALAB, Havana, Cuba). Animals were individually housed at the animals’ facility of the Center for Genetic Engineering and Biotechnology, Havana, Cuba, and maintained under controlled environmental conditions and light cycles (12/12 hrs). Rats were fed with standard laboratory rodent’s chow under no restriction. Following an acclimation week, the dorsum of the rats was conditioned to receive two controlled full-thickness wounds, under sodium pentobarbital (30 mg/kg) anesthesia. The cuts were generated with disposable 6 mm diameter punch biotomes (Acuderm, Ft. Lauderdale, USA). Two independent experiments were performed using the above described wound model. Thus, 10 rats ( wounds) were used for either GHRP-6 formulation or vehicle (1% CMC) groups in each experiment. Upon wounds induction the rats were randomly assigned to either group. The wounds were cleansed daily with saline, their contours traced on transparent plastic sheets and treated accordingly. Treatments were topically applied twice a day at the same hours during four days. Wounds closure dynamic was measured by planimetric analysis as described previously [16] using the ImageJ software, version 1.46r. Since the GHRP-6 intervention increased the rate of closure, the animals were terminated by anesthesia overdose on day five after wounding. Ulcers and a surrounding margin of intact skin (~5 mm) were collected and hemisectioned. One hemisection was preserved in RNA Later solution for further gene expression studies. The other hemisection was fixed in 10% buffered formalin, paraffin embedded, and 5-μm sectioned. The specimens were stained with hematoxylin/eosin (H/E) and Mallory trichrome to examine collagen deposit. Other slides were destined for immunohistochemistry (as described below).
Observation reveals that peptides have become more and more popular in recent years among bodybuilders and those coveting a great body. This trend, perhaps, is influenced by relative difficulty in getting and using anabolic steroids. But what are these substances and are they really legal alternatives to steroids? What benefits do bodybuilders hope to get from using them? We answer these questions and more, including peptide types, in this piece.
MGF stands for mechano growth factor—a peptide derived from insulin-like growth factor-1 (IGF-1), which plays a large role in childhood development and continues to have anabolic effects throughout adulthood. MGF has the ability to encourage repair and growth of wasted tissue through the activation of muscle stem cells, thereby increasing the synthesis of proteins necessary for tissue growth. This peptide is ideal of anyone suffering from muscle loss, either due to old age or a particular condition (i.e., HIV, cancer, etc.)
Among the other reasons why bodybuilders use peptides is its ability to help you recover faster. They assist in making oxygen available to the muscle cells in sufficient amount. They also improve user’s level of endurance. These benefits make them popular among athletes generally. Peptides further help to burn body fat, which is another reason they are considered beneficial in bodybuilding.

If you’re ready to see differences in your workout regimen, you may be curious how muscle peptides are associated with lean muscle gain and strength building. As a locally owned and operated company, Muscle Peptides Australia is committed to helping our clients across Australia achieve their fitness goals. Contact us to unlock your body’s real potential.
Consistent with these data, our group observed a transient inotropic effect of about 15 minutes in both healthy and infarcted rabbits following a single GHRP-6 intravenous bolus (400 µg/kg). Echocardiography recordings indicated a 15%–20% elevation of the ejection fraction as an increase in shortening fraction (Juan Valiente Mustelier and Jorge Berlanga Acosta, unpublished observations, 2007). More recent studies based on isolated murine hearts that underwent periods of ischemia and reperfusion (I/R) confirm that pre- or posttreatments with hexarelin for instance prevented the intracellular disturbances in Ca+2 transients through recovery of p-PLB after the I/R insult.43 Other studies involving adult Wistar rat ventricular myocytes have confirmed the positive inotropic response induced by hexarelin and other secretagogue peptides that bind the GHS-R1a, which activates protein kinase C signaling cascade.44
Dose-wise, studies have shown that the body will release a decent amount of natural GH with a dose of only 100mcg (termed the SATURATION DOSE) injected subcutaneously or intramuscularly. Higher doses can be used up to 300-500mcg in a single shot but double the dose does not mean double the GH; the amount of release is not directly proportional and the ratio of release diminishes as the dose climbs. I personally find 250mcg to be my sweet spot and doesn’t cost too much to run a short cycle at that dose.
MuscleSport AlphaSRM Builds muscle and burns fat simultaneously* 4 research validated testosterone enhancers* 5 effective thermogenic compounds* Increases metabolic rate* Inhibits aromatase* Nitrosigine® for muscle-engorging pumps* Building or retaining muscle while simultaneously losing fat has been described as a near impossible task. This “body recompositioning” often requires a calorie deficit or surplus that may deprive your body of key muscle…
There is evidence of involvement of organised crime in supply of the substances. The substances are offered for sale via the internet. Many of the substances are promoted as safe alternatives to traditional performance enhancing substances such as the anabolic steroids. Suppliers are making unproven assertions about the efficacy and safety of the substances.
I have not used IGF-1 but I have used a stack of Ipamorelin and CJC 1295 no DAC. I did not do any lab tests before, during or after but definitely noticed increased fat loss and better sleep. I was not trying to increase muscle so there was no change to speak of for me. But you are not recommending their use even without IGF-1, is that correct? I do not compete in anything so WADA is not a concern.

This peptide is a modified fragment of hGH which contains the portion of the molecule that is believed to be responsible for hGH’s anti-obesity effects. The peptide has been shown to increase fat burning without the increase in blood sugar and growth rate that has been seen with hGH itself. AOD 9604 has been deemed safe for chronic use by the FDA, receiving Human GRAS status in 2014. In addition to its utility as an anti-obesity peptide, AOD 9604 has been shown to have very favorable cartilage repair and regenerative properties, especially when paired with peptide BPC 157.
Because the ligands of most GPCRs are unknown, assays for their activity generally have no positive controls. GHS-R, however, was known to bind several artificial ligands, such as GHRP-6 or hexarelin, providing a convenient positive control for constructing the assay system used to search for the endogenous ligand. A cultured cell line expressing the GHS-R was established and used to identify tissue extracts that could stimulate the GHS-R, as monitored by increases in intracellular Ca2+ levels. After screening several tissues, very strong activity by an endogenous ligand was unexpectedly found in stomach extracts (). The ligand was finally purified by reversed-phase HPLC (RP-HPLC) and named as ghrelin. The name “ghrelin” is based on “ghre,” a word root in Proto-Indo-European languages for “grow,” in reference to its ability to stimulate GH release. Ghrelin is a 28 amino acid peptide in which the serine 3 (Ser3) is n-octanoylated and this modification is essential for the activity of ghrelin (Fig. 2). Ghrelin is the first known case of a peptide hormone modified by a fatty acid. Rat and human ghrelins differ in only two amino acid residues. There is no structural homology between ghrelin and peptide GHSs such as GHRP-6 or hexarelin.
GHRPs are not simply surrogates of GHRH, instead GHRP-6 is an artificial activator of a separate newly discovered receptor called Growth Hormone Secretagogue Receptor (GHS-R). Soon Ghrelin was discovered, the endogenous ligand that binds to the GHS-R. Both Ghrelin and all the synthetic compounds such as GHRP-6 were termed "Growth Hormone Secretagogues" (GHSs). One side effect of GHRP-6 is a significant increase in appetite due to stimulating the release of Ghrelin, a peptide that is released naturally in the lining of the stomach that increases hunger and gastric emptying. Also, GHRP-6 causes stimulation of the anterior pituitary gland which causes an increase in Growth Hormone release. The increased amounts of Growth Hormone can cause the liver to secrete the hormone IGF-1, which improves the animal body’s ability to burn fat and build muscle. Since GHRP-6 acts directly on the feedback loop which signals the inhibition of Growth Hormone release, GHRP-6 can re-stimulate the production of Growth Hormone.
Paracetamol/caffeine formulations have a long-established safety and efficacy profile over 25 years of use as an open-sale medicine in major markets around the world. The paracetamol/caffeine combination analgesic was registered as a schedule 2 product in Australia and has been marketed since 2010. Since that time no new significant issues or potential risks have been reported.

Ghrelin is a potent stimulator of growth hormone secretion from the anterior pituitary gland. The ghrelin receptor is a G protein-coupled receptor, known as the growth hormone secretagogue receptor. Ghrelin binds to the GHSR1a splice-variant of this receptor which is present in high density in the hypothalamus, pituitary as well as vagal afferent cell bodies and vagal afferent endings throughout the gastro-intestinal tract.
One of the other uses for GHRP-6 is to kick start your own GH after a cycle, a dose of 200-500mcg 2x a day is sufficient to start your own GH; however, it does not mean your own GH levels will be where they were before you carried out your cycle, this is user dependent. It will certainly be a very useful addition to any hormonal cycles' PCT, as the increased IGF-1 levels it brings will greatly increase the chances of you holding on to any muscle you have gained.

As the name indicates, this peptide is a fragment of human growth hormone. It is more specifically a modified form of the amino acids 176-191 in the C-terminal section of the latter substance. Bodybuilders mainly use it enhance fat burning for improved and more noticeable muscle growth. For weight loss, HGH Fragment 176-191 is thought to be considerably more potent than regular growth hormone. It also offers anti-aging benefits as a result of positive effects on IGF-1 levels.

Hexarelin via CD36 occupation increases the expression of multiple genes involved in fatty acid mobilization in adipocytes toward the mitochondrial oxidative phosphorylation, and many of these upregulated genes are known targets of PPARγ. Consistent with this, electron microscopy of hexarelin-treated adipocytes reflects highly organized cristae formation that spans the entire width of mitochondria, with a concomitant cytochrome c oxidase activity enhancement. Although this signaling and activation cascade has not been described for myocardial cells so far, the potential existence of these phosphorylative and mitochondriogenic mechanisms in the heart, and its potential amplification by GHRP ligands, may eventually contribute to myocardial salvage during critical ischemia periods.47 In a more recent study based on a myocardial infarction model, and addressed to examine whether hexarelin treatment can compensate for ghrelin deficiency in ghrelin-knockout mice, the mortality within two weeks was significantly lower in the hexarelin (6.7%) and ghrelin groups (14.3%) than in the vehicle group (50%). Furthermore, hexarelin was more effective than ghrelin as judged by the ejection fraction and other LV-dependent physiological constants as dP/dt max and dP/dt min, which is a measure of LV global contractility.48


CJC1295 is a 30 amino acid peptide, which primarily functions as a growth hormone releasing hormone analogue (mimicking the effect of GHRH). It was initially invented to treat deep fat deposits in people, because it is known that having an increase in our own growth hormone levels will target this. It stimulates production of our own growth hormone from the pituitary gland.
Ipamorelin is a pentapeptide, meaning that it is composed of five amino acids, that mimics the body’s natural GH release.  Ipamorelin is a growth hormone releasing peptide (GHRP) and analogue of the hormone Ghrelin. It induces GH release and increases the number of somatarophs(cells responsible for GH release) in a GH pulse by suppressing somatostatin.

Growth Hormone Releasing Peptide-6 or GHRP-6 is basically a hgH secretagoue, which has the potential to facilitate the effective increase the levels of natural secretion of hgH in our body. At the same time, this compound can also facilitate a sudden increase in body mass and bring about a massive reduction in body fat. GHRP-6 also includes artificial d-amino acids which lead the body to release growth hormones as well. GHRP-6 is not known to work well with GHRH, so it works at the Ghrelin's receptor in place of that receptor.
When taking Ipamorelin, you want it to be pushed through your system naturally, and at the same levels. If you are constantly altering the times you take it, or increase/decrease dosages during your cycle, this is not going to be attainable. To maximize the benefits and gains you are going to experience, dosage levels should be consistent, as should the timing of the dosage you are taking each day.

In June 2005, the NDPSC decided to reschedule pantoprazole from Schedule 4 to Schedule 3 when in oral preparations containing 20 mg or less of pantoprazole for the relief of heartburn and other symptoms of gastro-oesophageal reflux disease (GORD), in packs containing not more than 14 days' supply. This decision was based on the available efficacy and safety data which supported a Schedule 3 entry.
When taking Ipamorelin, you want it to be pushed through your system naturally, and at the same levels. If you are constantly altering the times you take it, or increase/decrease dosages during your cycle, this is not going to be attainable. To maximize the benefits and gains you are going to experience, dosage levels should be consistent, as should the timing of the dosage you are taking each day.
These substances come in form of powder that has to be reconstituted with sterilized water and injected. The injections are given either subcutaneously or intramuscularly, but the former option is more common. The advice is to use an insulin syringe for administration purpose. You need to be extra careful when self-injecting peptides. Make sure you do not strike a vital blood vessel.

SARMs stimulate androgen receptors specifically in muscle and bone cells, hence assisting with muscle and bone growth, while having little effect on the other cells in the body (unlike regular steroids). They have a special affinity for certain tissues like muscle and bone, but not for others, like the prostate, liver, and brain. This means more rapid muscle and bone growth without unwanted growth in other parts of your body.


In this one you have a peptide with potential to stimulate GH release without resulting in issues associated with others. Just like GHRP-6, it both stimulates the pituitary and suppresses somatostatin. This is not the most powerful growth hormone releasing peptide. But neither causes your appetite to surge drastically nor your prolactin or cortisol levels to rise. These reasons make them a favorite for some users.

In August 2010, the delegate confirmed the decisions of the June 2010 meeting of the NDPSC to transfer leflunomide to Appendix L. Appendix L was a new appendix created to list all of the requirements for dispensing labels previously included in the body of the Poisons Standard (i.e. paragraph 45, Dispensed Medicines, of Part 3, Miscellaneous Regulations) as part of the transitional amendments required to change the Standard for the Uniform Scheduling of Drugs and Poisons No. 24 into the Standard for the Uniform Scheduling of Medicines and Poisons No. 1, under the revised scheduling arrangements commencing 1 July 2010.
When you increase the dosage gradually it is also going to ensure you do not experience all (or any) of the noted side effects which are possible with the use of Ipamorelin. And, if you are taking other peptides, supplements, or growth hormones, it is the best way to ensure they are going to acclimate well and work together well, in order for you to realize the greatest results possible when trying to increase muscle mass, and lean muscle tissue, without putting on body fat in the process.
As a result, a general guideline for the purpose of achieving performance and physique enhancement is that of 100mcg administered three times per day. Each injection should be spaced evenly apart in order to achieve substantial HGH levels throughout the day due to the short half-life of GHRP-6 as well as the pulsatile manner of the HGH release that it causes. For greater results that would include more pronounced muscle gain and fat loss, more frequent injections would be required above the three times per day protocol. More details concerning the specific administration timing will be described shortly.
Combined, the loss of muscle and bone mass, is a quick ticket to the grave. The lack of supporting muscle and bone tissue, means that falls are more likely to occur, lengthy hospital stays inevitable, and the immobility created from these sustained injuries, produce further reduction in muscle mass and bone mass. A vicious cycle, which can be stopped in its tracks through the use of peptides such as SARMs.
GHRPs are not simply surrogates of GHRH, instead GHRP-6 is an artificial activator of a separate newly discovered receptor called Growth Hormone Secretagogue Receptor (GHS-R). Soon Ghrelin was discovered, the endogenous ligand that binds to the GHS-R. Both Ghrelin and all the synthetic compounds such as GHRP-6 were termed "Growth Hormone Secretagogues" (GHSs). One side effect of GHRP-6 is a significant increase in appetite due to stimulating the release of Ghrelin, a peptide that is released naturally in the lining of the stomach that increases hunger and gastric emptying. Also, GHRP-6 causes stimulation of the anterior pituitary gland which causes an increase in Growth Hormone release. The increased amounts of Growth Hormone can cause the liver to secrete the hormone IGF-1, which improves the animal body’s ability to burn fat and build muscle. Since GHRP-6 acts directly on the feedback loop which signals the inhibition of Growth Hormone release, GHRP-6 can re-stimulate the production of Growth Hormone.
Now these artificially manufactured compounds can replicate certain hormones within the human body to signal or trigger certain effects. Whereas GH (a total protein hormone of 191 amino acids), can attach to receptors at multiple sites within the body to influence different effects (say muscle cells, bone cells and fats cells, to name but three), shorter peptides have been isolated to trigger certain effects in a specific area/s. Imagine it’s like having a full tool box which you can mend a whole car with, but then you take certain tools out for different jobs and keep them apart in separate drawers which do specific jobs…sort of.
Django Nathan, a medical doctor with a degree in molecular biology and genetics, takes peptides because of his busy lifestyle: "Quite a few doctors I know are using them because they have so many beneficial effects and so few side effects. We're not elite athletes – we live rushed lives that can involve 70 hour weeks so staying fit and getting good sleep is essential – and peptides aid that."
Very tough to say. I am not a doctor and this is not to be taken, interpreted or construed as medical advice. Please talk with a licensed medical professional about this. These are just my own personal thoughts and not a prescription or a diagnosis or any form of health care whatsoever. I could possibly help but would need to see your health history, blood, biomarkers, etc. I'd be happy to help you via a personal one-on-one consult. Just go to https://bengreenfieldfitness.com/coaching. and then choose a 20 or 60 minute consult, whichever you'd prefer. I can schedule ASAP after you get that.
A multicenter study comparing the oral GH secretagogue macimorelin with arginine/GHRH found it to be safe, convenient, and of comparable efficacy (82% sensitivity, 92% specificity, and 87% accuracy in diagnosing adult GHD), with a GH cut-off point of 6.8 μg/L for patients with a body mass index (BMI) <30 kg/m2 and 2.7 µg/L for patients with a BMI >30 kg/m2 [268].
The T α 1 peptide can be administered via subcutaneous injection or as a transdermal cream. T α 1 has been found to be very safe, and there have not been any documented side effects associated with its administration. It is approved in more than 37 countries for the treatment of hepatitis B, hepatitis C, and as an adjunct to chemotherapy and various vaccines.

In June 2005, the NDPSC decided to reschedule pantoprazole from Schedule 4 to Schedule 3 when in oral preparations containing 20 mg or less of pantoprazole for the relief of heartburn and other symptoms of gastro-oesophageal reflux disease (GORD), in packs containing not more than 14 days' supply. This decision was based on the available efficacy and safety data which supported a Schedule 3 entry.
This particular peptide offers therapeutic benefits similar to those of hGH. CJC 1295 is a growth hormone releasing hormone (GHRH) analogue. In other words, it is a molecule that serves the same purpose as does GHRH—the hormone that stimulates the anterior pituitary to release hGH. However, unlike GHRH, which has a half-life of only minutes after IV administration, CJC 1295 is able to remain active in the body for extended periods due to its ability to bind to a protein in the blood known as albumin and avoid degradation by various enzymes. CJC 1295 increases an important growth factor, IGF-1, in addition to hGH, leading to fat loss, lean muscle growth, and enhanced sleep.

Manipulation of somatostatin tone also affects the GH response to GHSs. When hexarelin was given to subjects in combination with somatostatin, the amount of GH released was significantly reduced. When arginine, a postulated inhibitor of somatostatin, was administered to older adults, a group proposed to have increased somatostatin tone, GH levels following the administration of GHRP-6 increased significantly, to levels seen in younger subjects.


After repeated intravenous (i.v.) boluses of growth hormone-releasing peptide-6 (GHRP-6) we found recently increases of growth hormone (GH), corticotropin (ACTH) and cortisol levels and of the amount of stage 2 sleep. In clinical use, oral (p.o.), intranasal (i.n.) and sublingual (s.l.) routes of administration have advantages over i.v. administration. We compared the sleep-endocrine effects of 300 microg/kg of body weight (b.w.) GHRP-6 in enteric-coated capsules given p.o. at 21.00 h and of 30 microg/kg GHRP-6 i.n. or 30 microg/kg GHRP-6 sl. given at 22.45 h in normal young male controls with placebo conditions. After GHRP-6 p.o. secretion of GH, ACTH and cortisol remained unchanged. The only effect of GHRP-6 s.l. was a trend toward an increase in GH in the first half of the night. GHRP-6 i.n. prompted a significant increase in GH concentration during the total night and a trend toward an increase in ACTH secretion during the first half of the night, whereas cortisol secretion remained unchanged. Furthermore, after GHRP-6 i.n., sleep stage 2 increased in the second half of the night by trend, and spectral analysis of total night non-rapid eye movement (REM) sleep revealed a decrease of delta power by trend. In contrast sleep stage 2 decreased during the second half of the night after GHRP-6 p.o. Our data demonstrate that GHRP-6 is capable of modulating GH and ACTH secretion as well as sleep. However, the effects depend upon dosage, duration and route of administration.
×