MuscleSport AlphaSRM Builds muscle and burns fat simultaneously* 4 research validated testosterone enhancers* 5 effective thermogenic compounds* Increases metabolic rate* Inhibits aromatase* Nitrosigine® for muscle-engorging pumps* Building or retaining muscle while simultaneously losing fat has been described as a near impossible task. This “body recompositioning” often requires a calorie deficit or surplus that may deprive your body of key muscle…
You’re no doubt taking it for the fairy tale positive side effects, which have already been outlined, but like any caper about something enchanted, the magic comes with a price. For GHRP6 these can include flu-like symptoms, joint aches, headaches and water retention. Prolonged use can give you a tingling feeling in your skin than can also lead to a loss of sensitivity to touch. Yeah, you don’t want it down there. Fortunately, this is often in rare cases and when you consider even garden-variety paracetamol can dish out hives, diarrhoea and nausea then by comparison these aren’t huge risk factors. The biggest drawback is that it has a meagre half-life of 15-60 minutes, which means you have to take it daily for it to be effective, with the primary method of administration being a big ole fat needle. So the idea of turning the glutes into something that resembles nanna’s pincushion may deter pretty much all-conscientious pain objectors.
But let’s say you’ve already implemented the IGF-1 boosting strategies of adequate calories, sufficient protein, weight training, plenty of sleep, smart supplementation, mineral intake and alcohol moderation. Should you take the next step, wander into an anti-aging clinic, find an online pharmacy, lurk in the depths of bodybuilding forums, and begin IGF-1 injections?
Boasting similar structure as CJC-1295, sermorelin is commonly used for anti-aging purposes. But it is also considered useful for muscle building. It accounts for 29 amino acids of the 44 that make up growth hormone releasing hormones. This peptide is very potent for improving HGH levels, as shown in studies. It was observed that the 1-29 amino acid chain is mainly responsible for the ability of GHRH to stimulate release of growth hormone by the pituitary. However, sermorelin has very short half-life of about 10 minutes or less.
"I Ordered PH400 , both my training partner and I have trained for a few years now and thought lets try something new. We only did one bottle each. We increased our eating (clean) and within a week we were already training twice a day 4 times a week after a month i had put on approx 5kg (1-1.5kg muscle) . I recovered almost overnight and my ability to up weight between sets was definately a motivator and it wasnt just a pump after workouts it would actually stay. Even after being off it i had to ease off the training a my body couldn't push as much and recover in time , but we willl definatley begetting back on it again this time for a full 3 months and do a full stack. Would definately recommend PH and there is no taste i added it to my morning shake just one vile a day for 30 days , wouldnt need anymore than that. Also there were no side effects , but to see best results you want to train more often and increase food intake." Daniel Ram
The other submission commented on the consideration to place AOD-9604 in Appendix D. The submission supported listing in Schedule 4, but raised concerns that listing the substance in Appendix D would limit any future development work, including clinical trials that are currently being conducted on the substance. The submitter notes that there are currently 5 clinical trials notified to the TGA using this substance , with these approved clinical trials going ahead on the basis that the substance is safe for human use. Inclusion in Appendix D may place unnecessary burden on those conducting these clinical trials.
A remarkable specific (125)I-Tyr-Ala-hexarelin binding was observed in the human cardiovascular system where the highest binding levels were detected in ventricles, followed by atria, aorta, coronaries, carotid, endocardium, and vena cava. In other experiments on H9c2, cardiomyocyte-specific GHRP binding was found along with a potent antiapoptotic activity.3 The primarily investigated receptor was the growth hormone secretagogue receptor type 1a (GHS-R1a), which was detected in isolated human cardiomyocytes, myocardium, and aorta samples.17 It has been recently shown that GHS-R1a is a sort of “promiscuous receptor” involved in many systems and behavioral patterns such as reward, feeding, and memory, which makes it an attractive pharmacological target.18 Years later, the synthetic GHRP hexarelin was acknowledged as a ligand of another protein identified as CD36, a scavenger receptor that is expressed in various tissues, including monocytes/macrophages and the endothelial microvasculature. Activation of CD36 in perfused hearts by hexarelin was shown to increase coronary perfusion pressure in a dose-dependent manner. Contrariwise, this effect was lacking in hearts from CD36-null mice and hearts from spontaneous hypertensive rats genetically deficient in CD36.19,20 Thus, it is currently accepted that two cardiac receptor subtypes mediate the pharmacological actions of GHRP-6, GHRP-2, and hexarelin.21,22